"Your Friend is Sad" is a trademark of Jason Anarchy Games. The game is a copyright of Jason Anarchy Games and Shen Comix with upcoming guest cards being used with permission from their respective creators.
No, it's about typical sadness that everyone feels sometimes. If you feel more than that, this game probably isn't for you. There are some great resources on the page if you are looking for help with sadness that is more serious.
Don't see the answer to your question? Ask the project creator directly.