Yes and No. The 2015 Last Spike is quite different from the original. While the scope of the game and the theme are similar, the key difference is that the newer game does not use dice to determine what players can do. Instead players have more control of their options, and make meaningful decisions each turn, increasing strategy.
The 1976 game was positioned as a family game; this 2015 edition is designed to appeal to strategy gamers, eurogamers, train gamers, and is still suitable for families.