We know a few people who are colorblind ourselves. Each house color also has a unique shape (in the corner of each card) to help differentiate for those players who have a tough time distinguishing colors.
The game is recommended for ages 5+, but we play-tested with ages 3+. Younger players who aren't familiar with turn-based games may struggle. However, the special cards add an additional wrinkle to the game where any player (young or old) would benefit from a good memory. As the number of players increases, the complexity of the game increases, and resource scarcity comes into play!
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