Nox Archaist will run on original Apple II hardware (128k enhanced Apple //e, Apple IIc, and Apple IIGS) and Apple II emulators. For real hardware you'll need either dual floppy drives or a hard drive (such as the CFFA3000 or FloppyEMU).
While Nox Archaist should run on Apple II emulators on any platform, including Linux, Raspberry Pi, and Nintendo Wii, our testing is focused on physical Apple II hardware and emulators on the Mac and Windows PC platforms.
Update: Informal testing by a community volunteer has been done on Arch Linux (2019.05.01), Manjaro Linux (18.0.4), and Ubuntu (19.04), all using the microM8 emulator with Mockingboard music enabled. He reports that he did not encounter any problems. While Linux is not an officially supported platform, hopefully this backer's report will provide useful information for anyone who is interested in running Nox Archaist on Linux.