Not at all! La Mancha does not assume that players have knowledge of the book, and almost none of our playtesters had read the book when they played it. A willingness to battle monsters and fight for one's love, however, is highly recommended.
The teacher's guide can be downloaded as a PDF by copying and pasting this URL into your browser:
A goal for the game is to eventually have it translated into Spanish by an experienced translator. We are researching the cost associated with this process and will update backers as we learn more.
Don't see the answer to your question? Ask the project creator directly.