There will be NPCs since towns need citizens, structures need guards, crafters need leather as well as other NPCs but they will not be dropping tokens, items, etc. However, you will be able to scavenge/skin/etc. materials from them only. There is also a difference between PvE-NPCs (cows) and RvR-NPCs (guards, human or otherwise). I also promise that there will not be PvE expansions with new tiers of gear drops that become required to complete. This game is a RvR-focused MMORPG and will remain such.